Across TCGA patient cohorts, IPO9 protein abundance is significantly associated with the RNA expression of many other genes, with 14,974 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO9-associated genes across cancer lineages are CHEK1, ASPM, and GINS1. Each is linked with IPO9 in more than 9 cancer types. Because this analysis shows association rather than direction, both IPO9-to-partner and partner-to-IPO9 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO9→partner) and Y-score (partner→IPO9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHEK1 →	+1.082	+0.387	<.001	<.001	3	10
GBM	ASPM →	+1.303	+0.360	<.001	<.001	3	10
GBM	GINS1 →	+1.140	+0.422	<.001	<.001	3	9
LSCC	RFC5 →	+0.774	+0.273	<.001	<.001	3	9
HNSC	MCM3 →	+0.784	+0.226	.001	.001	3	9
GBM	NEK2 →	+1.160	+0.357	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,974 associations by consensus.

Exploration

IPO9 survival (RNA) · tumor vs normal (RNA) · all IPO9 data types