IPO7P1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IPO7P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,063 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IPO7P1-associated GO terms across cancer lineages are Interstrand cross-link repair, Protein K63-linked deubiquitination, and Protein modification by small protein removal. Each is linked with IPO7P1 in more than 21 cancer types. Because this analysis shows association rather than direction, both IPO7P1-to-partner and partner-to-IPO7P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interstrand cross-link repair grouped by IPO7P1-low versus IPO7P1-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO7P1→partner) and Y-score (partner→IPO7P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
DLBCInterstrand cross-link repair →+0.074+0.097<.001<.001321
DLBCProtein K63-linked deubiquitination →+0.053+0.105<.001.007122
DLBCProtein modification by small protein removal →+0.063+0.157<.001.003320
DLBC5S class rRNA transcription by RNA polymerase III →+0.078+0.077<.001.007221
DLBCDNA-templated transcription initiation →+0.071+0.092<.001.001221
DLBCGolgi organization →+0.066+0.107<.001<.001320
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,063 associations by consensus.

Interstrand cross-link repair by IPO7P1 expression — DLBC

Box plot of Interstrand cross-link repair in IPO7P1-low vs IPO7P1-high samples in DLBC.

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Exploration