Across TCGA patient cohorts, IPO7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,513 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO7-associated proteins across cancer lineages are RRM1, WEE1, and CDK7. Each is linked with IPO7 in more than 6 cancer types. Because this analysis shows association rather than direction, both IPO7-to-partner and partner-to-IPO7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO7→partner) and Y-score (partner→IPO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RRM1 →	+0.469	+0.511	<.001	<.001	3	7
LSCC	WEE1 →	+0.520	+0.607	<.001	<.001	3	5
HNSC	CDK7 →	+0.250	+0.866	<.001	.004	3	5
HNSC	GMPPA →	-0.343	-0.981	<.001	.003	3	5
UCEC	ADA2 →	-0.470	-0.459	<.001	.006	3	5
OV	C11orf58 →	+0.248	+0.353	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,513 associations by consensus.

Exploration

IPO7 survival (RNA) · tumor vs normal (RNA) · all IPO7 data types