Across TCGA patient cohorts, IPO7 protein abundance is significantly associated with the RNA expression of many other genes, with 13,559 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO7-associated genes across cancer lineages are MTCH2, FLI1, and CBX7. Each is linked with IPO7 in more than 7 cancer types. Because this analysis shows association rather than direction, both IPO7-to-partner and partner-to-IPO7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO7→partner) and Y-score (partner→IPO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTCH2 →	+0.490	+0.251	<.001	<.001	3	8
GBM	FLI1 →	-0.614	-0.239	<.001	<.001	3	8
BRCA	CBX7 →	-0.864	-0.429	<.001	<.001	3	7
PDAC	ASPA →	-0.690	-0.200	<.001	<.001	3	7
GBM	KIF18A →	+0.973	+0.247	.001	.002	3	7
GBM	NCAPG2 →	+0.903	+0.246	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,559 associations by consensus.

Exploration

IPO7 survival (RNA) · tumor vs normal (RNA) · all IPO7 data types