Across TCGA patient cohorts, IPO7 mutation is significantly associated with the RNA expression of many other genes, with 3,836 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IPO7-associated genes across cancer lineages are LINC00410, SLC36A1, and NPAP1P7. Each is linked with IPO7 in more than 2 cancer types. Because this analysis shows association rather than direction, both IPO7-to-partner and partner-to-IPO7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO7→partner) and Y-score (partner→IPO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00410 →	+0.134	+4.568	.001	.004	3	3
UCEC	SLC36A1 →	+0.463	+1.748	<.001	.002	3	3
LIHC	NPAP1P7 →	+0.030	+5.676	<.001	.001	3	2
CESC	GJE1 →	+0.037	+3.475	<.001	.008	3	2
CESC	CCDC12P1 →	+0.059	+4.342	<.001	.007	3	2
HNSC	TRAJ28 →	+0.347	+2.940	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,836 associations by consensus.

Exploration

IPO7 survival (RNA) · tumor vs normal (RNA) · all IPO7 data types