Across TCGA cell cohorts, IPO7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,109 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IPO7-associated GO terms across cancer lineages are Transcription by RNA polymerase I, Telomere tethering at nuclear periphery, and Transcription initiation at RNA polymerase I promoter. Each is linked with IPO7 in more than 16 cancer types. Because this analysis shows association rather than direction, both IPO7-to-partner and partner-to-IPO7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO7→partner) and Y-score (partner→IPO7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transcription by RNA polymerase I →	+0.098	+1.047	<.001	<.001	3	17
OVARY	Telomere tethering at nuclear periphery →	+0.180	+1.061	<.001	<.001	3	15
LARGE_INTESTINE	Transcription initiation at RNA polymerase I promoter →	+0.124	+0.754	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	'de novo' IMP biosynthetic process →	+0.174	+1.124	<.001	<.001	3	13
KIDNEY	Protein import into nucleus →	+0.073	+0.740	.004	.001	3	13
OVARY	Mitotic spindle assembly →	+0.088	+1.055	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,109 associations by consensus.

Exploration

IPO7 survival (RNA) · tumor vs normal (RNA) · all IPO7 data types