IPO5

Across TCGA patient cohorts, IPO5 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,058 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO5-associated proteins across cancer lineages are CUL4A, DIS3, and TPP2. Each is linked with IPO5 in more than 8 cancer types. Because this analysis shows association rather than direction, both IPO5-to-partner and partner-to-IPO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPO5 versus CUL4A in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO5→partner) and Y-score (partner→IPO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CUL4A →	+0.307	+0.397	<.001	<.001	3	9
LSCC	DIS3 →	+0.328	+0.755	<.001	<.001	3	8
OV	TPP2 →	+0.269	+0.467	<.001	<.001	3	7
GBM	GTF2F2 →	+0.569	+0.471	<.001	<.001	3	7
GBM	RBM26 →	+0.386	+0.509	<.001	<.001	3	6
LSCC	SPIN1 →	+0.419	+0.691	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,058 associations by consensus.

IPO5 vs CUL4A — OV

Explore this scatter interactively →