IPO5

Across TCGA patient cohorts, IPO5 protein abundance is significantly associated with the RNA expression of many other genes, with 17,546 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO5-associated genes across cancer lineages are DIAPH3, CARS2, and BORA. Each is linked with IPO5 in more than 7 cancer types. Because this analysis shows association rather than direction, both IPO5-to-partner and partner-to-IPO5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPO5 versus DIAPH3 in UCEC, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO5→partner) and Y-score (partner→IPO5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DIAPH3 →	+0.810	+0.226	<.001	.001	3	8
UCEC	CARS2 →	+0.591	+0.321	<.001	<.001	2	8
OV	BORA →	+0.687	+0.254	<.001	<.001	3	7
OV	TEX30 →	+0.632	+0.247	<.001	<.001	3	7
HNSC	NUFIP1 →	+0.544	+0.348	.002	<.001	3	7
LSCC	UGGT2 →	+0.633	+0.307	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,546 associations by consensus.

IPO5 vs DIAPH3 — UCEC

Explore this scatter interactively →