IPO13

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, IPO13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,318 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IPO13-associated GO terms across cancer lineages are RISC complex assembly, Pre-miRNA processing, and Microtubule nucleation. Each is linked with IPO13 in more than 14 cancer types. Because this analysis shows association rather than direction, both IPO13-to-partner and partner-to-IPO13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RISC complex assembly grouped by IPO13-low versus IPO13-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO13→partner) and Y-score (partner→IPO13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHRISC complex assembly →+0.129+0.879<.001<.001315
STOMACHPre-miRNA processing →+0.124+0.947<.001<.001314
STOMACHMicrotubule nucleation →+0.105+1.120.001<.001313
OVARYPositive regulation of protein localization to centrosome →+0.100+0.569<.001<.001312
SKINCytosolic transport →+0.060+0.734.001<.001312
STOMACHRegulation of protein localization to centrosome →+0.080+0.737.003.002311
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,318 associations by consensus.

RISC complex assembly by IPO13 expression — STOMACH

Box plot of RISC complex assembly in IPO13-low vs IPO13-high samples in STOMACH.

Explore this box plot interactively →

Exploration