IPO11

Across TCGA patient cohorts, IPO11 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,440 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IPO11-associated proteins across cancer lineages are CWC27, MSH2, and NASP. Each is linked with IPO11 in more than 5 cancer types. Because this analysis shows association rather than direction, both IPO11-to-partner and partner-to-IPO11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPO11 versus CWC27 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IPO11→partner) and Y-score (partner→IPO11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CWC27 →	+0.357	+0.391	<.001	<.001	3	6
LSCC	MSH2 →	+0.399	+0.383	<.001	<.001	3	6
GBM	NASP →	+0.402	+0.227	<.001	<.001	3	6
LSCC	RFC2 →	+0.377	+0.385	<.001	<.001	3	5
LSCC	CDC5L →	+0.243	+0.402	<.001	<.001	3	5
OV	DHFR →	+0.578	+0.440	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,440 associations by consensus.

IPO11 vs CWC27 — OV

Explore this scatter interactively →