IPMK

Across TCGA patient cohorts, IPMK protein abundance is significantly associated with the RNA expression of many other genes, with 1,487 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IPMK-associated genes across cancer lineages are CRABP2, TUBA1A, and ADAP2. Each is linked with IPMK in more than 1 cancer types. Because this analysis shows association rather than direction, both IPMK-to-partner and partner-to-IPMK results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IPMK versus CRABP2 in UCEC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPMK→partner) and Y-score (partner→IPMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CRABP2 →	-2.526	-0.467	<.001	.006	3	2
PDAC	TUBA1A →	-0.679	-0.498	<.001	.005	3	2
BRCA	ADAP2 →	-0.650	-0.434	<.001	<.001	3	2
PDAC	GAL3ST4 →	-0.641	-0.713	<.001	<.001	3	2
PDAC	HAUS4P1 →	-0.566	-0.614	.004	.001	3	2
CCRCC	MRPS2 →	-1.116	-0.684	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,487 associations by consensus.

IPMK vs CRABP2 — UCEC

Explore this scatter interactively →