IPMK

Across TCGA cell cohorts, IPMK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,450 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IPMK-associated GO terms across cancer lineages are Inositol phosphate metabolic process, Positive regulation of mitochondrial ATP synthesis coupled electron transport, and Phosphatidylinositol metabolic process. Each is linked with IPMK in more than 12 cancer types. Because this analysis shows association rather than direction, both IPMK-to-partner and partner-to-IPMK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Inositol phosphate metabolic process grouped by IPMK-low versus IPMK-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IPMK→partner) and Y-score (partner→IPMK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Inositol phosphate metabolic process →	+0.082	+0.897	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.112	+0.839	<.001	<.001	3	12
STOMACH	Phosphatidylinositol metabolic process →	+0.064	+1.086	.003	<.001	3	10
STOMACH	Protein modification by small protein removal →	+0.056	+1.019	.004	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Protein autoubiquitination →	+0.046	+0.646	.003	.002	3	8
OVARY	Establishment of mitotic sister chromatid cohesion →	+0.098	+0.536	.009	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,450 associations by consensus.

Inositol phosphate metabolic process by IPMK expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →