IPCEF1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, IPCEF1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated IPCEF1 data layer compared with 25 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in sarcoma (SARC), where higher IPCEF1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated IPCEF1 expression acts as an unfavorable survival marker.

SARC, CESC, and LIHC are the cancer types where IPCEF1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SARCDFSMedianAll0.1210.611.0416view →
CESCOSMedianAll0.1490.593.0156view →
LIHCOSMedianIII,IV0.2700.732.0216view →
COADOSMedianAll0.5380.873.0194view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

IPCEF1–SARC (DFS)

Kaplan–Meier survival curve for IPCEF1 mutant vs wild-type samples in SARC.

Open the SARC breakdown →

Exploration