IPCEF1

Across TCGA cell cohorts, IPCEF1 mutation is significantly associated with the RNA expression of many other genes, with 368 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IPCEF1-associated genes across cancer lineages are JOSD1, PRX, and SHOC2. Each is linked with IPCEF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IPCEF1-to-partner and partner-to-IPCEF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JOSD1 grouped by IPCEF1-low versus IPCEF1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IPCEF1→partner) and Y-score (partner→IPCEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	JOSD1 →	+0.624	+3.212	.002	.006	3	1
LARGE_INTESTINE	PRX →	+0.543	+3.212	.001	.006	3	1
LARGE_INTESTINE	SHOC2 →	+0.415	+3.212	.006	.006	3	1
LARGE_INTESTINE	RNGTT →	+0.504	+3.212	.007	.006	3	1
LARGE_INTESTINE	FBXL4 →	+0.501	+3.212	.003	.006	3	1
LARGE_INTESTINE	PCCB →	+0.654	+3.295	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 368 associations by consensus.

JOSD1 by IPCEF1 expression — LARGE_INTESTINE

Explore this box plot interactively →