IP6K1

Across TCGA patient cohorts, IP6K1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,309 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IP6K1-associated proteins across cancer lineages are CALR, HSP90B1, and KIAA1143. Each is linked with IP6K1 in more than 4 cancer types. Because this analysis shows association rather than direction, both IP6K1-to-partner and partner-to-IP6K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IP6K1 versus CALR in GBM, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K1→partner) and Y-score (partner→IP6K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CALR →	-0.389	-0.328	<.001	<.001	3	5
BRCA	HSP90B1 →	-0.319	-0.339	<.001	<.001	3	5
BRCA	KIAA1143 →	+0.409	+0.561	<.001	<.001	3	5
PDAC	QRICH1 →	+0.218	+0.297	<.001	<.001	3	5
GBM	PDIA5 →	-0.580	-0.310	<.001	<.001	3	4
BRCA	APPL1 →	+0.220	+0.447	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,309 associations by consensus.

IP6K1 vs CALR — GBM

Explore this scatter interactively →