IP6K1

Across TCGA patient cohorts, IP6K1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,788 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IP6K1-associated genes across cancer lineages are SAMM50, AKAP1, and ATP5IF1. Each is linked with IP6K1 in more than 2 cancer types. Because this analysis shows association rather than direction, both IP6K1-to-partner and partner-to-IP6K1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IP6K1 versus SAMM50 in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K1→partner) and Y-score (partner→IP6K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAMM50 →	-0.486	-0.137	.004	.003	3	3
UCEC	AKAP1 →	-0.584	-0.181	<.001	<.001	3	3
UCEC	ATP5IF1 →	-0.564	-0.151	.001	.001	3	3
UCEC	TOM1L1 →	-0.644	-0.172	<.001	.001	3	3
HNSC	PLPP2 →	-0.738	-0.176	.002	<.001	3	3
UCEC	CREB3L4 →	-1.028	-0.141	.004	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,788 associations by consensus.

IP6K1 vs SAMM50 — UCEC

Explore this scatter interactively →