IP6K1

Across TCGA patient cohorts, IP6K1 mutation is significantly associated with the RNA expression of many other genes, with 2,469 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IP6K1-associated genes across cancer lineages are RN7SKP181, RN7SL472P, and SNORD3B-2. Each is linked with IP6K1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IP6K1-to-partner and partner-to-IP6K1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP181 grouped by IP6K1-low versus IP6K1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IP6K1→partner) and Y-score (partner→IP6K1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RN7SKP181 →	+0.197	+5.087	.001	.002	3	2
COAD	RN7SL472P →	+1.412	+4.132	<.001	.001	3	2
UCEC	SNORD3B-2 →	+0.453	+1.673	.007	.007	3	2
BLCA	MIR4466 →	+0.418	+5.455	<.001	.001	3	1
BLCA	MIR941-5 →	+0.495	+4.314	<.001	.009	3	1
BLCA	MIR548C →	+0.393	+4.376	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,469 associations by consensus.

RN7SKP181 by IP6K1 expression — COAD

Explore this box plot interactively →