INTS9

Across TCGA patient cohorts, INTS9 mutation is significantly associated with the RNA expression of many other genes, with 2,170 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INTS9-associated genes across cancer lineages are LINC01281, RNA5SP419, and RNA5SP416. Each is linked with INTS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS9-to-partner and partner-to-INTS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01281 grouped by INTS9-low versus INTS9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS9→partner) and Y-score (partner→INTS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01281 →	+0.173	+1.692	.001	.001	3	2
UCEC	RNA5SP419 →	+0.329	+1.723	.008	.003	3	2
UCEC	RNA5SP416 →	+0.291	+1.870	.004	.001	3	2
UCEC	RNA5SP420 →	+0.355	+1.829	.001	.001	3	2
UCEC	MRC1 →	+0.485	+2.115	.002	<.001	3	2
HNSC	CASP3P1 →	+0.049	+4.578	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,170 associations by consensus.

LINC01281 by INTS9 expression — UCEC

Explore this box plot interactively →