INTS9

Across TCGA cell cohorts, INTS9 mutation is significantly associated with the RNA expression of many other genes, with 28 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INTS9-associated genes across cancer lineages are C2CD5, MOGAT1, and GNMT. Each is linked with INTS9 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS9-to-partner and partner-to-INTS9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C2CD5 grouped by INTS9-low versus INTS9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS9→partner) and Y-score (partner→INTS9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C2CD5 →	+0.773	+3.064	<.001	.009	3	1
LARGE_INTESTINE	MOGAT1 →	+0.075	+2.556	.004	.006	3	1
LARGE_INTESTINE	GNMT →	+0.237	+3.302	.002	.008	3	1
LARGE_INTESTINE	VWDE →	+1.417	+3.125	<.001	.008	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.005	+2.777	.003	.004	3	1
LARGE_INTESTINE	EOMES →	+0.444	+3.302	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

C2CD5 by INTS9 expression — LARGE_INTESTINE

Explore this box plot interactively →