INTS7

Across TCGA pan-cancer cohorts, INTS7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated INTS7 data layer compared with 23 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher INTS7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated INTS7 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where INTS7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.849	1.000	.005	22	view →
PDAC	DFS	Quartile	All	0.606	0.802	.010	16	view →
HNSC	OS	Quartile	All	0.776	0.950	.007	14	view →
LUAD	OS	Quartile	All	1.000	0.899	.016	7	view →
LSCC	DFS	Median	II,III,IV	0.873	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

INTS7–CCRCC (OS)

Open the CCRCC breakdown →