INTS7

Across TCGA patient cohorts, INTS7 mutation is significantly associated with the RNA expression of many other genes, with 1,762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INTS7-associated genes across cancer lineages are RAD51, BRCA1, and TRAJ28. Each is linked with INTS7 in more than 2 cancer types. Because this analysis shows association rather than direction, both INTS7-to-partner and partner-to-INTS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51 grouped by INTS7-low versus INTS7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS7→partner) and Y-score (partner→INTS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAD51 →	+0.619	+2.098	<.001	.002	3	3
UCEC	BRCA1 →	+0.523	+2.021	.001	.005	3	3
BLCA	TRAJ28 →	+0.612	+4.078	<.001	<.001	3	3
LUAD	RNU6-940P →	+0.595	+6.087	<.001	.002	3	2
CESC	TRIM49C →	+0.613	+4.966	<.001	<.001	3	2
CESC	TRAJ47 →	+0.536	+4.269	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,762 associations by consensus.

RAD51 by INTS7 expression — UCEC

Explore this box plot interactively →