INTS7

Across TCGA cell cohorts, INTS7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,161 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INTS7-associated GO terms across cancer lineages are Nuclear pore organization, Negative regulation of cell cycle phase transition, and Regulation of DNA-templated DNA replication initiation. Each is linked with INTS7 in more than 18 cancer types. Because this analysis shows association rather than direction, both INTS7-to-partner and partner-to-INTS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by INTS7-low versus INTS7-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS7→partner) and Y-score (partner→INTS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.193	+0.881	.002	.006	3	19
BLOOD_Myeloma	Negative regulation of cell cycle phase transition →	+0.068	+1.190	.007	.008	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication initiation →	+0.116	+0.939	<.001	<.001	3	17
CNS	Positive regulation of mRNA processing →	+0.110	+0.525	<.001	.001	3	16
KIDNEY	Spindle elongation →	+0.284	+0.794	<.001	.002	3	16
BONE	Nuclear pore complex assembly →	+0.172	+0.923	.004	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,161 associations by consensus.

Nuclear pore organization by INTS7 expression — BONE

Explore this box plot interactively →