INTS6L

Across TCGA cell cohorts, INTS6L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,513 significant associations in total. BONE shows the largest number of these associations.

The most reproducible INTS6L-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, Spliceosomal complex assembly, and Regulation of mRNA splicing, via spliceosome. Each is linked with INTS6L in more than 12 cancer types. Because this analysis shows association rather than direction, both INTS6L-to-partner and partner-to-INTS6L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cytoplasmic stress granule grouped by INTS6L-low versus INTS6L-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS6L→partner) and Y-score (partner→INTS6L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to cytoplasmic stress granule →	+0.132	+1.523	.002	<.001	3	13
OVARY	Spliceosomal complex assembly →	+0.109	+1.540	<.001	<.001	3	12
OVARY	Regulation of mRNA splicing, via spliceosome →	+0.089	+1.432	<.001	<.001	3	12
OVARY	Microtubule organizing center organization →	+0.065	+1.255	<.001	<.001	3	11
OVARY	Heterochromatin formation →	+0.071	+1.424	<.001	<.001	3	10
OVARY	Modulation of process of another organism →	+0.083	+1.522	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,513 associations by consensus.

Protein localization to cytoplasmic stress granule by INTS6L expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →