INTS6

Across TCGA patient cohorts, INTS6 protein abundance is significantly associated with the RNA expression of many other genes, with 11,378 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS6-associated genes across cancer lineages are TMEM97, PTPN22, and MTRF1. Each is linked with INTS6 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS6-to-partner and partner-to-INTS6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS6 versus TMEM97 in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS6→partner) and Y-score (partner→INTS6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TMEM97 →	+0.951	+0.137	<.001	<.001	3	6
LUAD	PTPN22 →	-0.831	-0.200	<.001	<.001	3	5
HNSC	MTRF1 →	+0.419	+0.218	.001	<.001	3	5
OV	EBPL →	+0.669	+0.267	.007	.004	3	5
OV	CKAP2 →	+0.854	+0.249	.001	.002	3	5
OV	NUDT15 →	+0.815	+0.311	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,378 associations by consensus.

INTS6 vs TMEM97 — LSCC

Explore this scatter interactively →