Across TCGA pan-cancer cohorts, INTS5 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated INTS5 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher INTS5 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated INTS5 expression acts as an unfavorable survival marker.

PDAC, COAD, and HNSC are the cancer types where INTS5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.633	0.966	<.001	48	view →
COAD	DFS	Median	III,IV	0.835	1.000	.033	18	view →
HNSC	OS	Quartile	All	0.786	0.958	.006	13	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: INTS5 tumor-vs-normal RNA expression · all INTS5 data types