INTS4P1

Across TCGA patient cohorts, INTS4P1 mutation is significantly associated with the RNA expression of many other genes, with 585 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INTS4P1-associated genes across cancer lineages are ARPP19P2, RNU6-178P, and ZNF595. Each is linked with INTS4P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS4P1-to-partner and partner-to-INTS4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARPP19P2 grouped by INTS4P1-low versus INTS4P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS4P1→partner) and Y-score (partner→INTS4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARPP19P2 →	+0.239	+2.839	.002	<.001	3	2
UCEC	RNU6-178P →	+0.753	+2.942	<.001	.005	3	2
UCEC	ZNF595 →	+0.901	+3.209	<.001	.009	3	1
UCEC	CWC25 →	+0.561	+3.491	.001	.002	3	1
UCEC	LINC02348 →	+0.394	+2.871	.001	.001	3	1
UCEC	ZNHIT3 →	+0.664	+3.480	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 585 associations by consensus.

ARPP19P2 by INTS4P1 expression — UCEC

Explore this box plot interactively →