INTS4

Across TCGA cell cohorts, INTS4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,661 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INTS4-associated GO terms across cancer lineages are Positive regulation of viral transcription, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, and Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with INTS4 in more than 14 cancer types. Because this analysis shows association rather than direction, both INTS4-to-partner and partner-to-INTS4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of viral transcription grouped by INTS4-low versus INTS4-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS4→partner) and Y-score (partner→INTS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of viral transcription →	+0.172	+0.497	<.001	<.001	3	15
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.121	+0.606	<.001	<.001	3	13
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.108	+0.603	<.001	<.001	3	13
BLOOD_Lymphoma	Centrosome cycle →	+0.069	+0.559	<.001	<.001	3	13
LARGE_INTESTINE	Centrosome duplication →	+0.087	+0.623	<.001	.001	3	12
URINARY_TRACT	Centriole replication →	+0.092	+0.956	.009	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,661 associations by consensus.

Positive regulation of viral transcription by INTS4 expression — BLOOD_Leukemia

Explore this box plot interactively →