INTS3

Across TCGA patient cohorts, INTS3 protein abundance is significantly associated with the RNA expression of many other genes, with 18,453 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS3-associated genes across cancer lineages are USP21, EEF1AKNMT, and DARS2. Each is linked with INTS3 in more than 6 cancer types. Because this analysis shows association rather than direction, both INTS3-to-partner and partner-to-INTS3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS3 versus USP21 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS3→partner) and Y-score (partner→INTS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	USP21 →	+0.718	+0.244	<.001	<.001	3	7
UCEC	EEF1AKNMT →	+1.111	+0.235	<.001	<.001	3	7
LSCC	DARS2 →	+0.787	+0.268	<.001	<.001	3	7
UCEC	DAP3 →	+0.745	+0.189	<.001	<.001	3	7
LSCC	CHTOP →	+0.580	+0.240	<.001	<.001	3	7
UCEC	FLAD1 →	+0.913	+0.181	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,453 associations by consensus.

INTS3 vs USP21 — LSCC

Explore this scatter interactively →