INTS3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, INTS3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,569 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible INTS3-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Cytosolic transport. Each is linked with INTS3 in more than 14 cancer types. Because this analysis shows association rather than direction, both INTS3-to-partner and partner-to-INTS3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by INTS3-low versus INTS3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS3→partner) and Y-score (partner→INTS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHNegative regulation of chromosome condensation →+0.171+0.982.001<.001315
LUNG_SCLCPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.150+0.791<.001.003315
STOMACHCytosolic transport →+0.078+0.810.005.004215
BONEPre-mRNA catabolic process →+0.242+0.962<.001<.001314
STOMACHPositive regulation of double-strand break repair →+0.091+0.878<.001<.001314
BONERegulatory ncRNA-mediated gene silencing →+0.091+1.025<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,569 associations by consensus.

Negative regulation of chromosome condensation by INTS3 expression — STOMACH

Box plot of Negative regulation of chromosome condensation in INTS3-low vs INTS3-high samples in STOMACH.

Explore this box plot interactively →

Exploration