INTS14

Across TCGA cell cohorts, INTS14 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible INTS14-associated genes across cancer lineages are OR10H5, KRTAP11-1, and C16orf82. Each is linked with INTS14 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS14-to-partner and partner-to-INTS14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10H5 grouped by INTS14-low versus INTS14-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS14→partner) and Y-score (partner→INTS14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR10H5 →	+0.012	+4.977	<.001	.007	3	1
SKIN	KRTAP11-1 →	+0.022	+5.415	<.001	.004	3	1
SKIN	C16orf82 →	+0.016	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR10H5 by INTS14 expression — SKIN

Explore this box plot interactively →