INTS13

Across TCGA pan-cancer cohorts, INTS13 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated INTS13 data layer compared with 27 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher INTS13 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated INTS13 expression acts as an unfavorable survival marker.

HNSC, LUAD, and CCRCC are the cancer types where INTS13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	IV	0.576	0.957	.002	39	view →
LUAD	OS	Median	II,III,IV	0.387	0.798	.001	20	view →
CCRCC	OS	Median	All	0.905	0.984	.032	17	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

INTS13–HNSC (DFS)

Open the HNSC breakdown →