INTS13

Across TCGA cell cohorts, INTS13 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INTS13-associated genes across cancer lineages are RHBDL3, DDX4, and TUB. Each is linked with INTS13 in more than 1 cancer types. Because this analysis shows association rather than direction, both INTS13-to-partner and partner-to-INTS13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RHBDL3 grouped by INTS13-low versus INTS13-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS13→partner) and Y-score (partner→INTS13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RHBDL3 →	+0.461	+3.295	.002	.006	3	1
LARGE_INTESTINE	DDX4 →	+0.031	+2.839	<.001	.004	3	1
LARGE_INTESTINE	TUB →	+1.157	+3.304	.001	.008	3	1
LARGE_INTESTINE	ABCG4 →	+0.379	+3.674	<.001	.001	3	1
LARGE_INTESTINE	ABCD2 →	+0.083	+3.054	.005	.001	3	1
LARGE_INTESTINE	FAM241A →	+1.088	+3.082	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

RHBDL3 by INTS13 expression — LARGE_INTESTINE

Explore this box plot interactively →