INTS12

Across TCGA patient cohorts, INTS12 protein abundance is significantly associated with the RNA expression of many other genes, with 11,919 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible INTS12-associated genes across cancer lineages are HEATR1, POLR1B, and COLEC12. Each is linked with INTS12 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS12-to-partner and partner-to-INTS12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS12 versus HEATR1 in UCEC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS12→partner) and Y-score (partner→INTS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HEATR1 →	+0.568	+0.171	<.001	<.001	3	6
HNSC	POLR1B →	+0.590	+0.193	<.001	<.001	3	6
COAD	COLEC12 →	-1.135	-0.290	<.001	<.001	3	6
LSCC	INTS6 →	+0.532	+0.191	.001	.001	3	5
OV	PTGIR →	-0.705	-0.288	<.001	<.001	3	5
HNSC	CCDC138 →	+0.673	+0.260	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,919 associations by consensus.

INTS12 vs HEATR1 — UCEC

Explore this scatter interactively →