INTS12

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, INTS12 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,735 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible INTS12-associated GO terms across cancer lineages are DAMP biosynthetic process, Purine deoxyribonucleoside monophosphate biosynthetic process, and Nuclear pore organization. Each is linked with INTS12 in more than 11 cancer types. Because this analysis shows association rather than direction, both INTS12-to-partner and partner-to-INTS12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAMP biosynthetic process grouped by INTS12-low versus INTS12-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS12→partner) and Y-score (partner→INTS12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASDAMP biosynthetic process →+0.167+0.761<.001<.001312
PANCREASPurine deoxyribonucleoside monophosphate biosynthetic process →+0.167+0.761<.001<.001312
SKINNuclear pore organization →+0.077+0.521.006<.00139
PANCREASCOPII-coated vesicle cargo loading →+0.072+0.461.005.00239
PANCREASCMP biosynthetic process →+0.113+0.466.001.004210
LUNG_SCLCBox C/D sno(s)RNA 3'-end processing →+0.121+0.450.009.003111
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,735 associations by consensus.

DAMP biosynthetic process by INTS12 expression — PANCREAS

Box plot of DAMP biosynthetic process in INTS12-low vs INTS12-high samples in PANCREAS.

Explore this box plot interactively →

Exploration