INTS10

Across TCGA patient cohorts, INTS10 protein abundance is significantly associated with the RNA expression of many other genes, with 19,812 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INTS10-associated genes across cancer lineages are NCAPH, CCNB2, and SPAG5. Each is linked with INTS10 in more than 5 cancer types. Because this analysis shows association rather than direction, both INTS10-to-partner and partner-to-INTS10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INTS10 versus NCAPH in GBM, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS10→partner) and Y-score (partner→INTS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCAPH →	+0.621	+0.191	<.001	<.001	3	6
BRCA	CCNB2 →	+0.889	+0.218	.003	<.001	3	6
LSCC	SPAG5 →	+0.825	+0.162	<.001	<.001	3	6
GBM	RFC3 →	+0.870	+0.263	<.001	<.001	3	6
HNSC	CDCA2 →	+0.995	+0.255	<.001	<.001	3	6
BRCA	CDK5RAP1 →	+0.442	+0.195	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,812 associations by consensus.

INTS10 vs NCAPH — GBM

Explore this scatter interactively →