INTS10

Across TCGA cell cohorts, INTS10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,225 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INTS10-associated GO terms across cancer lineages are Negative regulation of sister chromatid cohesion, piRNA-mediated gene silencing by mRNA destabilization, and tRNA transcription. Each is linked with INTS10 in more than 11 cancer types. Because this analysis shows association rather than direction, both INTS10-to-partner and partner-to-INTS10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of sister chromatid cohesion grouped by INTS10-low versus INTS10-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INTS10→partner) and Y-score (partner→INTS10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of sister chromatid cohesion →	+0.141	+1.125	.005	.002	2	12
OVARY	piRNA-mediated gene silencing by mRNA destabilization →	+0.189	+0.721	<.001	.001	3	11
BONE	tRNA transcription →	+0.130	+0.740	.008	.001	3	10
LUNG_NSCLC_LUAD	tRNA transcription by RNA polymerase III →	+0.077	+0.758	<.001	<.001	3	10
BREAST	Telomeric D-loop disassembly →	+0.065	+0.864	<.001	<.001	3	9
CNS	Positive regulation of telomere capping →	+0.100	+0.514	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,225 associations by consensus.

Negative regulation of sister chromatid cohesion by INTS10 expression — STOMACH

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