INSYN2B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INSYN2B mutation is significantly associated with the RNA expression of many other genes, with 3,696 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INSYN2B-associated genes across cancer lineages are RNA5SP507, CDY3P, and GUSBP16. Each is linked with INSYN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both INSYN2B-to-partner and partner-to-INSYN2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2B→partner) and Y-score (partner→INSYN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
READRNA5SP507 →+0.412+3.909.003.00732
READCDY3P →+0.030+5.691<.001<.00132
READGUSBP16 →+0.335+4.400<.001.00232
READMIR4744 →+0.619+4.023.003.00532
READMIR7976 →+0.660+3.827<.001.00632
LIHCRNU6-198P →+0.279+5.008<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,696 associations by consensus.

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