Across TCGA patient cohorts, INSYN2B mutation is significantly associated with the total protein of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INSYN2B-associated genes across cancer lineages are p27_pT157, eEF2, and A-Raf_pS299. Each is linked with INSYN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both INSYN2B-to-partner and partner-to-INSYN2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2B→partner) and Y-score (partner→INSYN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	p27_pT157 →	+0.197	+2.815	.013	.036	3	1
UCEC	eEF2 →	+0.385	+2.000	.016	.032	3	1
UCEC	A-Raf_pS299 →	-0.131	-3.169	.015	.019	3	1
UCEC	GAPDH →	+0.601	+2.999	.012	.035	3	1
UCEC	GATA6 →	-0.143	-1.992	.040	.031	3	1
UCEC	INPP4B →	-0.310	-3.169	.033	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

INSYN2B survival (RNA) · tumor vs normal (RNA) · all INSYN2B data types