Across TCGA cell cohorts, INSYN2B mutation is significantly associated with the RNA expression of many other genes, with 209 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INSYN2B-associated genes across cancer lineages are SYT10, OR1L3, and MAGEB10. Each is linked with INSYN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both INSYN2B-to-partner and partner-to-INSYN2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSYN2B→partner) and Y-score (partner→INSYN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	SYT10 →	+0.516	+5.217	<.001	<.001	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	MAGEB10 →	+0.097	+4.095	<.001	.009	3	1
SKIN	GLRA4 →	+0.040	+4.467	<.001	.004	3	1
SKIN	OR2T4 →	+0.019	+4.415	<.001	.007	3	1
SKIN	OR1P1 →	+0.016	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 209 associations by consensus.

Exploration

INSYN2B survival (RNA) · tumor vs normal (RNA) · all INSYN2B data types