INSRR

Across TCGA patient cohorts, INSRR protein abundance is significantly associated with the RNA expression of many other genes, with 12,203 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible INSRR-associated genes across cancer lineages are CXCL1, AQP9, and ABI3BP. Each is linked with INSRR in more than 5 cancer types. Because this analysis shows association rather than direction, both INSRR-to-partner and partner-to-INSRR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSRR versus CXCL1 in UCEC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INSRR→partner) and Y-score (partner→INSRR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL1 →	-2.328	-0.278	<.001	.002	3	6
HNSC	AQP9 →	-1.449	-0.435	<.001	<.001	3	5
BRCA	ABI3BP →	+1.037	+0.212	<.001	<.001	3	5
HNSC	FPR2 →	-1.205	-0.456	<.001	<.001	3	5
BRCA	PRELP →	+1.561	+0.278	<.001	<.001	3	5
BRCA	GAS7 →	+0.973	+0.268	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,203 associations by consensus.

INSRR vs CXCL1 — UCEC

Explore this scatter interactively →