INSM2

Across TCGA patient cohorts, INSM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,297 significant associations in total. GBM shows the largest number of these associations.

The most reproducible INSM2-associated proteins across cancer lineages are PCYT1A_S323, MAP4_S853, and PHF2_S905. Each is linked with INSM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both INSM2-to-partner and partner-to-INSM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INSM2 versus PCYT1A_S323 in LSCC, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM2→partner) and Y-score (partner→INSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PCYT1A_S323 →	-0.823	-0.135	<.001	<.001	3	4
HNSC	MAP4_S853 →	-0.910	-0.186	<.001	<.001	3	4
LSCC	PHF2_S905 →	+0.600	+0.079	<.001	.001	2	4
PDAC	COPA_S402 →	-0.950	-0.115	<.001	.001	3	3
CCRCC	RIOK2 →	-0.373	-0.172	<.001	<.001	3	3
PDAC	RUFY1_S165 →	-0.575	-0.161	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,297 associations by consensus.

INSM2 vs PCYT1A_S323 — LSCC

Explore this scatter interactively →