INSM2

Across TCGA cell cohorts, INSM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 898 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible INSM2-associated GO terms across cancer lineages are Collagen metabolic process, Regulation of monocyte aggregation, and Positive regulation of monocyte aggregation. Each is linked with INSM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both INSM2-to-partner and partner-to-INSM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Collagen metabolic process grouped by INSM2-low versus INSM2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INSM2→partner) and Y-score (partner→INSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Collagen metabolic process →	-0.139	-1.239	.001	.006	3	6
LUNG_NSCLC_LUSC	Regulation of monocyte aggregation →	-1.138	-0.035	<.001	.002	3	5
LUNG_NSCLC_LUSC	Positive regulation of monocyte aggregation →	-1.138	-0.035	<.001	.002	3	5
LUNG_NSCLC_LUSC	Regulation of dendritic cell antigen processing and presentation →	-0.883	-0.033	.002	.005	3	5
BLOOD_Myeloma	Maintenance of protein location in nucleus →	+0.061	+0.206	<.001	.009	3	4
BLOOD_Lymphoma	Positive regulation of monoatomic ion transport →	-0.043	-0.105	.009	.009	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 898 associations by consensus.

Collagen metabolic process by INSM2 expression — LUNG_SCLC

Explore this box plot interactively →