INSL4

Across TCGA cell cohorts, INSL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 452 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible INSL4-associated GO terms across cancer lineages are Positive regulation of eating behavior, Regulation of glycolytic process through fructose-6-phosphate, and Negative regulation of glycolytic process through fructose-6-phosphate. Each is linked with INSL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both INSL4-to-partner and partner-to-INSL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of eating behavior grouped by INSL4-low versus INSL4-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INSL4→partner) and Y-score (partner→INSL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of eating behavior →	+0.999	+1.763	<.001	<.001	3	3
LUNG_NSCLC_LUAD	Regulation of glycolytic process through fructose-6-phosphate →	-0.090	-1.546	<.001	.002	3	3
LUNG_NSCLC_LUAD	Negative regulation of glycolytic process through fructose-6-phosphate →	-0.090	-1.546	<.001	.002	3	3
LUNG_NSCLC_LUAD	Potassium ion import across plasma membrane →	+0.143	+1.334	<.001	.003	3	3
LUNG_NSCLC_LUAD	Sodium ion homeostasis →	+0.160	+1.333	<.001	.003	3	3
LUNG_NSCLC_LUAD	Vitamin catabolic process →	+0.134	+1.523	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 452 associations by consensus.

Positive regulation of eating behavior by INSL4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →