Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, INSIG1 mutation is significantly associated with the RNA expression of many other genes, with 3,607 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible INSIG1-associated genes across cancer lineages are HIKESHI, MRPL57, and RPL27P8. Each is linked with INSIG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both INSIG1-to-partner and partner-to-INSIG1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (INSIG1→partner) and Y-score (partner→INSIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.