INPPL1

Across TCGA patient cohorts, INPPL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,126 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible INPPL1-associated proteins across cancer lineages are PPME1, NUMA1, and CRELD2. Each is linked with INPPL1 in more than 4 cancer types. Because this analysis shows association rather than direction, both INPPL1-to-partner and partner-to-INPPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPPL1 versus PPME1 in HNSC, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INPPL1→partner) and Y-score (partner→INPPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPME1 →	+0.384	+0.723	.001	.001	3	5
HNSC	NUMA1 →	+0.385	+0.706	<.001	<.001	3	4
LSCC	CRELD2 →	-0.479	-0.515	<.001	<.001	3	4
PDAC	PTK7 →	+0.351	+0.265	<.001	.001	3	4
COAD	SYTL1 →	-0.688	-0.850	<.001	<.001	3	4
LSCC	GMPS →	+0.328	+0.368	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,126 associations by consensus.

INPPL1 vs PPME1 — HNSC

Explore this scatter interactively →