INPPL1

Across TCGA patient cohorts, INPPL1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,812 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible INPPL1-associated genes across cancer lineages are LAMTOR1, MRAS, and CLPB. Each is linked with INPPL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both INPPL1-to-partner and partner-to-INPPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, INPPL1 versus LAMTOR1 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPPL1→partner) and Y-score (partner→INPPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LAMTOR1 →	+0.853	+0.361	<.001	<.001	3	8
HNSC	MRAS →	+0.874	+0.240	<.001	<.001	3	5
HNSC	CLPB →	+0.548	+0.238	<.001	<.001	3	5
LSCC	FAM168A →	+0.651	+0.391	<.001	<.001	3	5
HNSC	RNF121 →	+1.012	+0.350	<.001	<.001	3	5
LSCC	RAB6A →	+0.577	+0.256	.003	.005	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,812 associations by consensus.

INPPL1 vs LAMTOR1 — HNSC

Explore this scatter interactively →