INPPL1

Across TCGA cell cohorts, INPPL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,664 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible INPPL1-associated GO terms across cancer lineages are Endosomal transport, Negative regulation of autophagy, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with INPPL1 in more than 16 cancer types. Because this analysis shows association rather than direction, both INPPL1-to-partner and partner-to-INPPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by INPPL1-low versus INPPL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (INPPL1→partner) and Y-score (partner→INPPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Endosomal transport →	+0.074	+1.657	<.001	<.001	3	17
STOMACH	Negative regulation of autophagy →	+0.084	+1.192	<.001	.009	3	16
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.189	+1.354	.001	.004	3	16
UPPER_AERODIGESTIVE_TRACT	Stress granule assembly →	+0.154	+1.546	<.001	<.001	3	16
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.209	+1.024	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA splicing, via spliceosome →	+0.113	+1.820	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,664 associations by consensus.

Endosomal transport by INPPL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →