INPP5F

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, INPP5F mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible INPP5F-associated genes across cancer lineages are ASNS, Caspase-7-cleavedD198, and Caveolin-1. Each is linked with INPP5F in more than 2 cancer types. Because this analysis shows association rather than direction, both INPP5F-to-partner and partner-to-INPP5F results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5F→partner) and Y-score (partner→INPP5F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECASNS →+0.435+2.087<.001.00433
UCECCaspase-7-cleavedD198 →+0.595+1.434.001.02733
BLCACaveolin-1 →-0.835-2.999.007.03532
UCECMEK1 →+0.334+2.392.003<.00132
UCECmTOR_pS2448 →-0.103-1.571.025.03232
UCECRad50 →-0.229-1.765.002.01332
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration