Across TCGA cell cohorts, INPP5F mutation is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible INPP5F-associated genes across cancer lineages are CHCHD4, TECRL, and IL31. Each is linked with INPP5F in more than 1 cancer types. Because this analysis shows association rather than direction, both INPP5F-to-partner and partner-to-INPP5F results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5F→partner) and Y-score (partner→INPP5F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CHCHD4 →	+0.522	+3.067	.008	.009	3	2
LARGE_INTESTINE	TECRL →	+0.008	+2.754	.002	.009	3	2
CNS	IL31 →	+0.031	+4.981	<.001	.008	3	1
SKIN	OTOF →	+0.175	+3.665	<.001	.001	3	1
SKIN	TRIM50 →	+0.044	+3.648	.003	.002	3	1
SKIN	PRORY →	+0.480	+2.688	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

Exploration

INPP5F survival (RNA) · tumor vs normal (RNA) · all INPP5F data types