Across TCGA patient cohorts, INPP5B RNA expression is significantly associated with the protein abundance of many other proteins, with 11,996 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible INPP5B-associated proteins across cancer lineages are MRPL32, MRPL47, and MRPL53. Each is linked with INPP5B in more than 4 cancer types. Because this analysis shows association rather than direction, both INPP5B-to-partner and partner-to-INPP5B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (INPP5B→partner) and Y-score (partner→INPP5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRPL32 →	-0.393	-0.370	<.001	<.001	3	5
LUAD	MRPL47 →	-0.366	-0.401	<.001	<.001	3	5
OV	MRPL53 →	-0.493	-0.430	<.001	.004	3	5
PDAC	ADPRS →	+0.403	+0.306	.003	<.001	3	5
OV	PPIF →	-0.740	-0.592	<.001	<.001	3	5
BRCA	MRPS5 →	-0.359	-0.453	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,996 associations by consensus.

Exploration

INPP5B survival (RNA) · tumor vs normal (RNA) · all INPP5B data types